According to officials, the fight took place at a home in the 19000 block of Poplar Ridge Road.
The two stabbing victims were taken to a local hospital, where they are reported to be in stable condition. Three other people at the party were also cut in the fray.
Police said the party crashers left the party after the fight. No suspects have been identified in the stabbing. It has also been reported that the crowd became unmanageable after some invited guests posted the location of the party to uninvited individuals online.
Anyone with information can call police at 301-352-1200 or submit a tip online.